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Effects of glial cell derived neurotrophic factor on colon glial cells in rats with slow t

78.6%),dizzy(10cases,71.4%)and dysarthria(10 cases,71.4%).Infarctions caused by atherosclerosis were found in35cases of LMI(72.9%)and12cases of MMI(85.7%).Five cases(10.4%)of LMI died in hospital,while1case(7.1%)of MMI died in hospital.No lesion was found in16cases(25.8%)by MRI-DWI within the first24hours of onset.Conclusion Our study showes that the mean onset age of LMI is older than that of MMI.The lesion of LMI is frequently located in the upper and middle medulla,whereas the lesion of MMI is mostly in the upper medulla.The prognosis of LMI is worse than that of MML.Atherosclerosis of the vertebral arteries is the predominant vascular pathology in MI.

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2016372Correlation between cerebrospinal fluid protein and facial paralysis in patients with Guillain-Barre syndrome.YANG Hong(杨红),et al.Dept Neurol,2nd Milit Med Univ,Shanghai200433.Chin J Nerv Ment Dis2016;42(3):141-144.

Objective To explore the correlation between the cerebrospinal fluid protein and facial paralysis in patients with Guillain-Barre syndrome(GBS).Methods Clinical and biochemical data of111patients with GBS in depart-ment of neurology from January2005to September2015 were retrospectively analyzed.GBS patients were divided into the normal and paralyzed groups.Their clinical and biochemical characteristics were compared between the two groups.According to level of cerebrospinal fluid pro-tein,GBS patients were divided into normal,mild high and severe high cerebrospinal fluid protein groups.Inci-dences of facial paralysis were compared among these three groups.The correlation between the cerebrospinal fluid protein and facial paralysis was analyzed.Results There was no significant difference in gender,age,re-spiratory infection and other clinical symptoms(P>0.05),whereas there were statistically significant differ-ences in cerebrospinal fluid protein,immunoglobulin G,and cerebrospinal fluid albumin/serum albumin ratio be-tween normal and paralysis groups(P<0.05).Among the three groups by different levels of cerebrospinal fluid protein,there were statistically significant differences in the incidence of facial paralysis(F=3.48,P=0.03).Cerebrospinal fluid protein was positively correlated with facial paralysis(r=0.288,P<0.01).Conclusion The incidence of facial paralysis is associated with the levels of cerebrospinal fluid protein.Thus,cerebrospinal fluid protein may be helpful in monitoring of GBS patients with facial paralysis.

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2016373The value of calcaneal quantitative ultra-sound(QUS)T score under-2.5in predicting stroke.WU Pengjia(武鹏佳),et al.Dept Endocrinol,Affili Hosp Guizhou Med Univ,Guiyang550004.Chin J Endocrinol Metab2016;32(5):395-398.

Objective To explore the relationship between risk of stroke and calcaneal quantitative ultrasound(QUS)T score under-2.5.Methods5847subjects over the age of40from Yunyan District,Guiyang City were investiga-ted with questionnaire,physical examination,blood lip-ids,other metabolic indexes and calcaneus bone density determination from May to October,2011using cluster sampling method and were followed up for3years.Sub-jects were divided into stroke group(99subjects)and non-stroke group(5748subjects)according to the oc-currence of stroke in the follow-up period.The relation-ship between risk of stroke and QUS T score under-2.5 was analyzed.Results Compared to the non-stroke group,the number of subjects with T score under-2.5 in calcaneal QUS was larger in the stroke group,the difference of which was statistically significant(P<0.05).T score of bone density under-2.5in calcaneal QUS was found to be an independent risk factor for pre-dicting stroke after adjusting for age,sex,and body mass index(HR=1.467,95%CI0.753-2.855).The rela-tionship between risk of stroke and T score under-2.5 in calcaneal QUS remained unchanged after further adjust ment of smoking,diabetes,education,and hypertension (HR=1.265,95%CI0.647-2.475).Conclusion The risk of stroke and T score of bone density under -2.5in calcaneal QUS was independently associated,and the latter is an independent risk factor for predicting stroke.

(Authors)

2016374Effects of glial cell derived neurotrophic factor on colon glial cells in rats with slow transit

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·China Medical Abstracts(Internal Medicine)

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