2013年专利过期化合物汇总

药物名称专利号

恩他卡朋 entacapone US5446194布林佐胺 Brinzolamide US5378703非索芬那定 Fexofenadine hydrochloride US5578610噻利考西 Celecoxib US5466823替莫唑胺 Temozolomide US5260291扎那米韦 Zanamivir US5360817罗非西布 Rofecoxib US5474995

US6239173盐酸阿洛司琼 Alosetron Hydrochloride US5360800唑来膦酸 Zoledronic acid US4939130卡泊芬净醋酸酯 Caspofungin acetate US5378804

US5792746度他雄胺 dutasteride US5998427厄他培南 Ertapenem US5652233盐酸度洛西汀 Duloxetine hydrochloride US5023269卡比多巴 Carbidopa US5446194帕立骨化醇 Paricalcitol US5587497阿瑞吡坦 aprepitant US5719147依替米贝 Ezetimibe USRE37721哌加他尼钠 pegaptanib sodium US5919455奥沙利铂 Oxaliplatin US5290961替加环素 tigecycline US5494903利塞磷酸钠 Risedronate Sodium US5583122奈拉滨 nelarabine US5424295依法韦恩茨 Efavirenz US5519021环索奈德 ciclesonide US5482934比马前列胺 Bimatoprost US6403649伊班膦酸钠 Ibandronate sodium US4927814卡巴拉汀 Rivastigmine US4948807

申请人专利期满日药品注册申请号Orion-yhtyma Oy (Espoo, FI)OCT 19,2013020796

Alcon Laboratories, Inc. (Fort Worth, TX)APR 01,2012020816

Albany Molecular Research, Inc. (Albany, NY)NOV 26,2013020872

G.D. Searle & Co. (Chicago, IL)NOV 30,2013020998

Cancer Research Campaign Technology Limited (London, GB2)AUG 11,2013021029

Biota Scientific Management Pty Ltd (Melbourne, AU)JUL 26,2013021036

Merck Frosst Canada, Inc. (Kirkland, CA)JUN 24,2013021042

Glaxo Group Limited (London, GB2)JAN 13,2013021107

Ciba-Geigy Corporation (Ardsley, NY)SEP 02,2012021223

Merck & Co., Inc. (Rahway, NJ)MAR 16,2013021227

Glaxo Wellcome Inc. (Research Triangle Park, NC)SEP 17,2013021251 Zeneca Limited (London, GB)FEB 02,2013 021319

Eli Lilly and Company (Indianapolis, IN)JUN 11,2013021332

Orion-yhtyma Oy (Espoo, FI)OCT 19,2013 021485 Wisconsin Alumni Research Foundation (Madison, WI)DEC 24,2013020819

Merck & Co., Inc. (Rahway, NJ)JUN 29,2012021549 Schering Corporation (Kenilworth, NJ)OCT 25,2016 021687 Enzon, Inc. (Piscataway, NJ)OCT 27,2013021756 Tanaka Kikinzoku Kogyo K.K. (JP)JAN 12,2013 021759 American Cyanamid Company (Wayne, NJ)AUG 13,2012021817

The Procter & Gamble Company (Cincinnati, OH)DEC 10,2013 021821 Burroughs Wellcome Co. (Research Triangle Park, NC)JUN 13,2012 021877 MERCK & CO INC (US)MAY 21,2013020972 ELMUQUIMICA FARM SL (ES)JAN 09,2013 021658 Allergan Sales, Inc. (Irvine, CA)SEP 21,2012021275 Boehringer Mannheim GmbH (Mannheim, DE)MAR 17,2012021455 Proterra AG (Zug, CH)AUG 14,2012020823

适应症药物信息帕金森氏病*

青光眼*

过敏症*

肿瘤、关节炎*

肿瘤*

流感*

关节炎*

妇女腹泻型肠易激综合症*

骨质疏松症，骨转移瘤*

抗真菌*

良性前列腺肥大症*

抗生素*

抑郁症*

帕金森氏病*

血液透析病人继发性甲状旁腺功能亢进*

化疗止吐*

降脂*

老年黄斑变性*

抗癌*

抗生素*

骨质疏松症*

白血病*

艾滋病*

哮喘*

青光眼、高眼压

骨质疏松症

阿尔茨海默氏病