持续静脉泵入咪达唑仑治疗小儿癫痫持续状态的疗效观察及护理

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持续静脉泵入咪达唑仑治疗小儿癫痫持续状态的疗效观察及护理

作者：彭伏梅

来源：《中国医学创新》2016年第36期

【摘要】目的：总结持续静脉泵入咪达唑仑治疗小儿癫痫持续状态的临床效果与护理。

方法：选取本院2014年4月-2015年4月收治的64例小儿癫痫持续状态患儿为研究对象，按照患儿收治顺序将其随机分为对照组和试验组，各32例。对照组患儿采用丙戊酸钠和5%葡萄糖溶解安定辅助治疗，且配合传统的常规护理；试验组患儿采用持续静脉泵入咪达唑仑进行治疗，且进行全面护理干预。对比两组患儿的发病时间、发病间隔、治疗总有效率、不良反应发生情况及患儿家属对护理工作满意度。结果：试验组患儿发病持续时间明显短于对照组，发病间隔长于对照组，差别均有统计学意义（P

【关键词】静脉泵入；咪达唑仑；小儿癫痫持续状态

【Abstract】 Objective：To summarize the clinical effect and nursing of continuous intravenous infusion of Midazolam in the treatment of children with epilepsy.Method：64 children with status epilepticus in our hospital from April 2014 to April 2015 were selected as the research objects，according to the order of children，they were randomly divided into the control group and the experimental group，each of 32 cases.The control group was treated with Sodium Valproate and 5% Glucose Solution dissolve Valium therapy，and combined with conventional nursing care，the experimental group was treated with continuous intravenous infusion of Midazolam，and the comprehensive nursing intervention was carried out.The time of onset，interval of onset，total effective rate，incidence of adverse reactions and family members’ satisfaction on nursing care of the two groups were compared.Result：The time of onset of the experimental group was significantly shorter than the control group，the interval of onset was longer than the control group，the differences were statistically significant（P

【Key words】 Intravenous infusion； Midazolam； Children with status epilepticus

First-author’s address：Central People’s Hospital of Ji’an，Ji’an 343000，China

doi：10.3969/j.issn.1674-4985.2016.36.021

癫痫是临床上常见的神经系统疾病，70%的患者在正规服药情况下，病情可以得到有效控制，但仍有部分患者服药效果不佳，癫痫频繁发作，对神经系统造成持续性的损伤。癫痫持续状态的发生更容易增加患儿身体疾病的发生率，对患儿的身心健康造成重大影响[1-2]。临床上传统治疗癫痫的药物有苯巴比妥、丙戊酸钠、地西泮等，存在副作用大、疗效不理想等问题，