42例子痫前期患者血清学指标与尿蛋白值变化及其临床意义

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42例子痫前期患者血清学指标与尿蛋白值变化及其临床意义

作者：张静罗小婉匡晓梅

来源：《上海医药》2016年第15期

摘要目的：探讨子痫前期血清学指标与尿蛋白值变化及其临床意义。方法：选取我院产科子痫前期孕妇42例作为研究组，同期选取正常孕妇40例作为对照组，采用ELISA方法检

测血清AST、ALT、GGT、TP、ALB、Urea、Cr、UA、b2-MG、LDH和24 h电泳检测尿蛋白UPRO，比较两组上述指标的差异。结果：研究组血清学指标（AST、ALT、GGT、Urea、Cr、UA、b2-MG、LDH）和尿蛋白值均明显高于对照组，血清TP、ALB均明显低于对照组，两组比较均有显著性差异。结论：上述指标可能参与子痫前期病情的发生。

关键词子痫前期血清尿蛋白值

中图分类号：R714.245 文献标识码：B 文章编号：1006-1533（2016）15-0040-03

The changes of serological indexes and urinary protein value in 42 cases of patients with preeclampsia and their clinical significance

ZHANG Jing*， LUO Xiaowan， KUANG Xiaomei

（Department of Gynecology， Boai Hospital of Zhongshan City， Zhongshan 528400，China）

ABSTRACT Objective： To explore the changes of serological indexes and urinary protein value in the patients with preeclampsia and their clinical significance. Methods： Forty-two cases of preeclampsia from our obstetric department were selected as a study group， and meanwhile 40 cases of normal pregnant women as a control group. Serological indexes such as AST， ALT， GGT，TP， ALB， Urea， Cr， UA， b2-MG and LDH， and UPRO value were detected by ELISA and electrophoresis， respectively. Differences of the above mentioned indexes were compared between the two groups. Results： The serological indexes including AST， ALT， GGT， Urea， Cr，UA， b2-MG and LDH and urinary protein value were significantly higher while serum TP and ALB were significantly lower in the study group than in the control group （P

KEY WORDS preeclampsia； serum； urinary protein

妊娠大于20周的孕妇出现高血压、蛋白尿和水肿症状称为子痫前期，合并全身器官损害，严重者出现脑出血、昏迷、胎盘早破、胎儿生长受限、胎死宫内、早产、心理衰竭、抽搐