抗癌相关药总结

Trade Name(s)ANGPT1/2(ANG1/2)

AMG 780

MEDI-3617

REGN910nesvacumab

RO5520985,RG7221

vanucizumab

B4GALNT1Ch14.18,ch14.18-UTC

dinutuximab

Unituxin BAFF belimumab

Benlysta CCR4KW-0761mogamulizum

ab

CD19MEDI-551inebilizumab

CD19/CD3MT103, MT-103, MEDI-

538blinatumomab

Blincyto GA101obinutuzumab

Gazyvaro IDEC-102,IDEC-C2B8

rituximab

Rituxan,Mabthera IDEC Y2B8ibritumomab

tiuxetan Zevalin drug can be bound via

tiuxetan to

111In or 90Y

TG-1101,

LFB-R603ublituximab

ofatumumab Arzerra,

HuMax-CD20

CD22

CAT-8015moxetumomab pasudotox CD27

CDX-1127varlilumab CD33

gemtuzumab Mylotarg CD37

TRU-016otlertuzumab daratumumab Darzalex,

HuMax-CD38

SAR650984CD52Campath alemtuzumab

ARGX-110SGN-70, h1F6vorsetuzumab

CD74hLL1milatuzumab

CD105TRC105,TRC-105, c-SN6j carotuximab

CD248(TEM1)MORAb-004

ontuxizumab

CEACAM5RG7813,RO6895882cergutuzumab

amunaleukin

CSF1R RG7155,RO5509554emactuzumab

CSF2KB003lenzilumab Therapeutic Antibodies

Target Development Name(s)Generic

Name(s)

Notes ANGPT2(ANG2)CD20CD38CD70

CP675,206

tremelimumab MDX-010,

MDX-101,

BMS-734016

ipilimumab Yervoy OMP-21M18

demcizumab OMP-305B83

navicixizumab EGFL7MEGF0444A parsatuzumab 1024 DS modotuximab ABT-806,mAb-806

depatuxizuma b ABX-EGF

panitumumab Vectibix h-R3,

TheraCIM nimotuzumab IMC-11F8

necitumumab Portrazza IMC-C225

cetuximab Erbitux MEHD7945 A

duligotuzumab MM-151

RO5083945,

GA201

imgatuzumab Sym004

futuximab FZD7OMP-18R5vantictumab GT-Mab 7.3-GEX

glycooptimized trastuzumab-GEX MGAH22

margetuximab MM-111

MOAB 2C4pertuzumab

Perjeta,Omnitarg trastuzumab Herceptin

AV 203LJM716MEHD7945 A duligotuzumab MM-111MM-121,SAR256212seribantumab MM-141istiratumab REGN1400U3-1287, AMG 888patritumab AMG 102rilotumumab AV-299,SCH900105ficlatuzumab AMG-479

ganitumab BI 836845

BIIB022

CP-751871

figitumumab IMC-A12

cixutumumab MEDI-573

dusigitumab MK-0646

dalotuzumab MM-141istiratumab

HER2(ERBB2/ne u)

HER3

(ERBB3)

HGFR

IGF-1R EGFR (HER1/ERB B1)CTLA4DLL4

BI 836845MEDI-573KIR

BMS-986015lirilumab LOXL2

AB0024, GS-6624simtuzumab ABT-700telisotuzumab LY2875358emibetuzumab MetMAb,R05490258,OA-5D onartuzumab MMP9

GS-5745andecaliximab NOTCH1

OMP-52M51brontictuzuma b NRP1

MNRP1685A vesencumab NT5E

MEDI9447oleclumab AMP-224BMS-936558,MDX-1106,ONO-4538nivolumab Opdivo CT-011pidilizumab MK-3475,lambrolizumab pembrolizuma b Keytruda MDX-1105,BMS-936559MEDI-4736durvalumab Imfinzi MPDL3280A,RG7446atezolizumab Tecentriq MSB0010718C,MSB0010682avelumab Bavencio IMC-3G3olaratumab Lartruvo MEDI-575tovetumab PIGF

ziv-aflibercept Zaltrap RANKL

denosumab Xgeva ROR1

UC-961cirmtuzumab SEMA4D

VX15/2503SLAMF7

(CS1/CD31

9/CRACC)

HuLuc63elotuzumab Empliciti TGFBR2

IMC-TR1BMS 663513urelumab PF-05082566TRAIL-

R1/DR4,R2/

D5

AMG951,rhApo2L/TRAI L dulanermin TRAIL-

R1/D4HGS-ETR1mapatumumab AMG-655conatumumab HGS-ETR2

lexatumumab LBY135

PRO95780apomab

bevacizumab Avastin

VEGFA IGF-2R

MET

PD-1

PD-L1

PDGFRα

TNFRSF9

(CD137/4-

1BB)TRAIL-

R2/D5

VEGFA

OMP-305B83navicixizumab

vanucizumab

RO5520985,

RG7221

ziv-aflibercept Zaltrap

VEGFB ziv-aflibercept Zaltrap VEGFC VGX-100

VEGFR2IMC-1121B ramucirumab Cyramza